Menke nitration

The Menke nitration is the nitration of electron rich aromatic compounds with cupric nitrate and acetic anhydride. The reaction introduces the nitro group predominantly in the ortho position to the activation group.[1] The reaction is named after the Dutch chemist J.B. Menke.[2]

Menke nitration
Named after J. B. Menke
Reaction type Substitution reaction

See also

References
  1. Wang Z (2009). "Menke Nitration". Comprehensive organic name reactions and reagents. Hoboken, N.J.: John Wiley. doi:10.1002/9780470638859.conrr425. ISBN 978-0-470-63885-9.
  2. Menke JB (1925). "Nitration with nitrates". Recueil des Travaux Chimiques des Pays-Bas. 44: 141. doi:10.1002/recl.19250440209.


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