MYLPF

Myosin light chain, phosphorylatable, fast skeletal muscle is a protein that in humans is encoded by the MYLPF gene.[5] It is located on chromosome 16 in humans. Myosin light chain, phosphorylatable, fast skeletal muscle is an integral part of the myosin light chain structure found in human muscles.

MYLPF
Identifiers
Aliases	MYLPF, HUMMLC2B, MRLC2, MYL11, MLC2B, myosin light chain, phosphorylatable, fast skeletal muscle
External IDs	OMIM: 617378 MGI: 97273 HomoloGene: 22728 GeneCards: MYLPF
Gene location (Human) Chr. Chromosome 16 (human)[1] Band 16p11.2 Start 30,370,934 bp[1] End 30,377,991 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7|7 F3 Start 127,208,890 bp[2] End 127,214,298 bp[2]
Gene ontology Molecular function • calcium ion binding • structural constituent of muscle • metal ion binding Cellular component • lysosomal membrane • cytosol • muscle myosin complex • myosin complex Biological process • muscle contraction • skeletal muscle tissue development • immune response Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	29895	17907
Ensembl	ENSG00000180209	ENSMUSG00000030672
UniProt	Q96A32	P97457
RefSeq (mRNA)	NM_013292 NM_001324458 NM_001324459	NM_016754 NM_001347655
RefSeq (protein)	NP_001311387 NP_001311388 NP_037424	NP_001334584 NP_058034
Location (UCSC)	Chr 16: 30.37 – 30.38 Mb	Chr 7: 127.21 – 127.21 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000180209 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000030672 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Myosin light chain, phosphorylatable, fast skeletal muscle".

Further reading

• Nudel U, Calvo JM, Shani M, Levy Z (Sep 1984). "The nucleotide sequence of a rat myosin light chain 2 gene". Nucleic Acids Research. 12 (18): 7175–86. doi:10.1093/nar/12.18.7175. PMC 320149. PMID 6091059.
• Garfinkel LI, Periasamy M, Nadal-Ginard B (Sep 1982). "Cloning and characterization of cDNA sequences corresponding to myosin light chains 1, 2, and 3, troponin-C, troponin-T, alpha-tropomyosin, and alpha-actin". The Journal of Biological Chemistry. 257 (18): 11078–86. PMID 6179945.
• Sachdev S, Raychowdhury MK, Sarkar S (Oct 2003). "Human fast skeletal myosin light chain 2 cDNA: isolation, tissue specific expression of the single copy gene, comparative sequence analysis of isoforms and evolutionary relationships". DNA Sequence. 14 (5): 339–50. doi:10.1080/1042517031000154952. PMID 14756420. S2CID 7284166.
• Amoresano A, Di Costanzo A, Leo G, Di Cunto F, La Mantia G, Guerrini L, Calabrò V (Apr 2010). "Identification of DeltaNp63alpha protein interactions by mass spectrometry". Journal of Proteome Research. 9 (4): 2042–8. doi:10.1021/pr9011156. PMID 20085233.