Kielmeyera variabilis
Kielmeyera variabilis (malva-do-campo or pau santo) is tree growing to a height of 3–6 meters, found in savannah regions of eastern and central Brazil (the Cerrado).[1] K. variabilis is traditionally used in folk medicine to treat tropical diseases including schistosomiasis, leishmaniasis, malaria, as well as fungal and bacterial infections.[2]
| Kielmeyera variabilis | |
|---|---|
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Scientific classification  | |
| Kingdom: | Plantae |
| Clade: | Tracheophytes |
| Clade: | Angiosperms |
| Clade: | Eudicots |
| Clade: | Rosids |
| Order: | Malpighiales |
| Family: | Calophyllaceae |
| Genus: | Kielmeyera |
| Species: | K. variabilis |
| Binomial name | |
| Kielmeyera variabilis | |
K. variabilis has been shown to contain three flavonols and a biflavone known to show antioxidant activity: quercitrin, quercetin-3-O-β-glucoside, quercetin-3-O-β-galactoside; and podocarpusflavone A (the biflavone).[3]
In 2019 a new acylphoroglucinol isolated from the branches of the tree showed activity against Methicillin-resistant Staphylococcus aureus (MRSA).[4]
Notes
- Ken Fern (2020). "Kielmeyera variabilis". Tropical Plants Database. Retrieved May 4, 2020.
- Alves TMA, Silva AF, Brandão M, Grandi TSM, Smânia EF, Smânia Jr A, Zani CL 2000. Biological screening of Brazilian medicinal plants. Mem Inst Oswaldo Cruz 95: 367-373.
- Coqueiro, Aline; Regasini, Luis; Skrzek, Scheila; Queiroz, Marcos; Silva, Dulce; da Silva Bolzani, Vanderlan (2013). "Free Radical Scavenging Activity of Kielmeyera variabilis (Clusiaceae)". Molecules. 18 (2): 2376–2385. doi:10.3390/molecules18022376. ISSN 1420-3049. PMC 6270038. PMID 23429348.
- Coqueiro, Aline; Choi, Young H.; Verpoorte, Robert; Gupta, Karthick B. S. S.; De Mieri, Maria; Hamburger, Matthias; Young, Maria C. M.; Stapleton, Paul; Gibbons, Simon; Bolzani, Vanderlan da S. (2016). "Antistaphylococcal Prenylated Acylphoroglucinol and Xanthones from Kielmeyera variabilis". Journal of Natural Products. 79 (3): 470–476. doi:10.1021/acs.jnatprod.5b00858. ISSN 0163-3864. PMID 26900954.
References
- Por, F.D. (2002). The Pantanal of Mato Grosso (Brazil): World's Largest Wetlands (Monographiae Biologicae). Springer. ISBN 0-7923-3481-7.
- Raffauf, Robert F. (1996). Plant Alkaloids: A Guide to Their Discovery and Distribution. Food Products Press. ISBN 1-56022-860-1.
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