Invasin

Invasins are a class of proteins associated with the penetration of pathogens into host cells.[1] Invasins play a role in promoting entry during the initial stage of infection.[2][3]

In 2007, Als3 was identified as a fungal invasin allowing Candida albicans to infect host cells.[4]

References
  1. "Invasin". Stedman’s Medical Dictionary. Wolters Kluwer Health.
  2. Isberg, Ralph R.; Voorhis, Deborah L.; Falkow, Stanley (1987). "Identification of invasin: A protein that allows enteric bacteria to penetrate cultured mammalian cells". Cell. 50 (5): 769–78. doi:10.1016/0092-8674(87)90335-7. PMID 3304658. S2CID 3125395.
  3. Pepe, J. C.; Miller, V. L. (1993). "Yersinia enterocolitica invasin: A primary role in the initiation of infection". Proceedings of the National Academy of Sciences of the United States of America. 90 (14): 6473–7. Bibcode:1993PNAS...90.6473P. doi:10.1073/pnas.90.14.6473. PMC 46954. PMID 8341658.
  4. Phan, Quynh T; Myers, Carter L; Fu, Yue; Sheppard, Donald C; Yeaman, Michael R; Welch, William H; Ibrahim, Ashraf S; Edwards, John E; Filler, Scott G (2007). "Als3 is a Candida albicans Invasin That Binds to Cadherins and Induces Endocytosis by Host Cells". PLOS Biology. 5 (3): e64. doi:10.1371/journal.pbio.0050064. PMC 1802757. PMID 17311474.
  • The dictionary definition of invasin at Wiktionary


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.