Hepatitis F virus

Hepatitis F is a hypothetical virus linked to viral hepatitis. Several hepatitis F candidates emerged in the 1990s; however, none of these claims were substantiated.[1][2][3]

This article is about the hypothetical virus. For the virus family Togavirus, see Togaviridae.
Main article: Hepatitis

In 1994, Deka et al. reported that novel viral particles had been discovered in the stool of post-transfusion, non-hepatitis A, non-hepatitis B, non-hepatitis C, non-hepatitis E patients.[4] Injection of these particles into the bloodstream of Indian rhesus monkeys caused hepatitis, and the virus was named hepatitis F or Toga virus. Further investigations failed to confirm the existence of the virus, and it was delisted as a cause for infectious hepatitis.[3][5]

A subsequently-discovered virus thought to cause hepatitis was named Hepatitis G, though its role in hepatitis has not been confirmed and it is now considered synonymous with GB virus C. It is an "orphan virus" with no causal links to any human disease.[6]

References
  1. Uchida, T. (1993). "Genetic Variations of the Hepatitis B Virus and Their Clinical Relevance". Microbiol. Immunol. 37 (6): 425–39. doi:10.1111/j.1348-0421.1993.tb03233.x. PMID 7694049.
  2. Fagan, E. A. (1994). "Acute Liver Failure of Unknown Pathogenesis: The Hidden Agenda". Hepatology. 19 (5): 1307–12. doi:10.1002/hep.1840190532. PMID 8175156.
  3. Bowden, S. (2001). "New Hepatitis Viruses: Contenders and Pretenders". J. Gastroenterol. Hepatol. 16 (2): 124–31. doi:10.1046/j.1440-1746.2001.02405.x. PMID 11207890.
  4. Deka N, Sharma MD, Mukerjee R (1994). "Isolation of the novel agent from human stool samples that is associated with sporadic non-A, non-B hepatitis". J. Virol. 68 (12): 7810–5. PMC 237242. PMID 7966570.
  5. Kelly, D.; Skidmore, S. (2002). "Hepatitis C-Z: recent advances". Arch. Dis. Child. 86 (5): 339–43. doi:10.1136/adc.86.5.339. PMC 1751087. PMID 11970925.
  6. Lefrère J. J.; Laperche, S.; Roudot-Thoraval, F. (April 2008). "Hepatitis G Virus: A Suitable Marker of in vivo Efficacy for Pathogen Inactivation". Vox Sang. 95 (1): 76–8. doi:10.1111/j.1423-0410.2008.01050.x. PMID 18393946.
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