Globotriosylceramide b-1,6-N-acetylgalactosaminyl-transferase
Globotriosylceramide beta-1,6-N-acetylgalactosaminyl-transferase (EC 2.4.1.79, globoside N-acetylgalactosaminyltransferase, uridine diphosphoacetylgalactosamine-glycosphingolipid acetylgalactosaminyltransferase, glycosphingolipid beta-N-acetylgalactosaminyltransferase, GalNAc transferase) is an enzyme with systematic name UDP-N-acetyl-D-galactosamine-globotriosylceramide beta-1,6-N-acetylgalactosaminyltransferase.[1] This enzyme catalyses the following chemical reaction
- UDP-N-acetyl-D-galactosamine + globotriosylceramide UDP + globotetraosylceramide
| Globotriosylceramide beta-1,6-N-acetylgalactosaminyl-transferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.1.154 | ||||||||
| CAS number | 62213-46-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The product has a terminal beta-N-acetylgalactosamine residue.
References
- Lockney MW, Sweeley CC (August 1982). "Characterization of a glycosphingolipid beta-N-acetylgalactosaminyl-transferase activity in cultured hamster (nil) cells". Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 712 (2): 234–41. doi:10.1016/0005-2760(82)90339-3. PMID 6812637.
External links
- Globotriosylceramide+beta-1,6-N-acetylgalactosaminyl-transferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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