GSDMC

Gasdermin C is a protein that in humans is encoded by the GSDMC gene. [5]

GSDMC
Identifiers
Aliases	GSDMC, MLZE, gasdermin C
External IDs	OMIM: 608384 MGI: 2146102 HomoloGene: 69487 GeneCards: GSDMC
Gene location (Human) Chr. Chromosome 8 (human)[1] Band 8q24.21 Start 129,748,196 bp[1] End 129,786,624 bp[1]
Gene location (Mouse) Chr. Chromosome 15 (mouse)[2] Band 15|15 D1 Start 63,824,346 bp[2] End 63,845,177 bp[2]
Gene ontology Molecular function • molecular function • phosphatidylserine binding • phosphatidylinositol-4,5-bisphosphate binding • phosphatidylinositol-4-phosphate binding Cellular component • cytoplasm • mitochondrion • microtubule organizing center • cytosol • cell membrane • membrane Biological process • programmed cell death • biological process • pyroptosis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	56169	331063
Ensembl	ENSG00000147697 ENSG00000285114	ENSMUSG00000056293
UniProt	Q9BYG8	Q2KHK6
RefSeq (mRNA)	NM_031415	NM_001168274 NM_177912
RefSeq (protein)	NP_113603	NP_001161746 NP_808580
Location (UCSC)	Chr 8: 129.75 – 129.79 Mb	Chr 15: 63.82 – 63.85 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. ENSG00000285114 GRCh38: Ensembl release 89: ENSG00000147697, ENSG00000285114 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000056293 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Gasdermin C". Retrieved 2016-08-26.

Further reading

• Saeki N, Usui T, Aoyagi K, Kim DH, Sato M, Mabuchi T, Yanagihara K, Ogawa K, Sakamoto H, Yoshida T, Sasaki H (2009). "Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium". Genes Chromosomes Cancer. 48 (3): 261–71. doi:10.1002/gcc.20636. PMID 19051310. S2CID 19705164.