GBP5

Guanylate binding protein 5 is a protein in humans that is encoded by the GBP5 gene. [5]

GBP5
Identifiers
Aliases	GBP5, GBP-5, guanylate binding protein 5
External IDs	OMIM: 611467 MGI: 2429943 HomoloGene: 14183 GeneCards: GBP5
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1p22.2 Start 89,258,950 bp[1] End 89,272,804 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 H1 Start 142,493,978 bp[2] End 142,522,344 bp[2]
Gene ontology Molecular function • nucleotide binding • GTP binding • GO:0001948 protein binding • hydrolase activity • GTPase activity • identical protein binding • protein homodimerization activity Cellular component • cytoplasm • Golgi membrane • Golgi apparatus • membrane • cytoplasmic vesicle • perinuclear region of cytoplasm Biological process • immune system process • positive regulation of cytokine production involved in inflammatory response • inflammatory response • positive regulation of NLRP3 inflammasome complex assembly • protein homotetramerization • positive regulation of innate immune response • cellular response to interferon-gamma • response to bacterium • protein localization to Golgi apparatus Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	115362	229898
Ensembl	ENSG00000154451	ENSMUSG00000105504
UniProt	Q96PP8	Q8CFB4
RefSeq (mRNA)	NM_052942 NM_001134486	NM_153564 NM_212440
RefSeq (protein)	NP_001127958 NP_443174	NP_705792
Location (UCSC)	Chr 1: 89.26 – 89.27 Mb	Chr 3: 142.49 – 142.52 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000154451 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000105504 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Guanylate binding protein 5". Retrieved 2013-01-23.

Further reading