Flavone apiosyltransferase
In enzymology, a flavone apiosyltransferase (EC 2.4.2.25) is an enzyme that catalyzes the chemical reaction
- UDP-apiose + 5,7,4'-trihydroxyflavone 7-O-beta-D-glucoside UDP + 5,7,4'-trihydroxyflavone 7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside]
| flavone apiosyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.4.2.25 | ||||||||
| CAS number | 37332-49-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are UDP-apiose and 5,7,4'-trihydroxyflavone 7-O-beta-D-glucoside, whereas its 3 products are UDP, 5,7,4'-trihydroxyflavone (apigenin), and [[7-O-[beta-D-apiosyl-(1->2)-beta-D-glucoside]]].
This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is UDP-apiose:5,4'-dihydroxyflavone 7-O-beta-D-glucoside 2-O-beta-D-apiofuranosyltransferase. Other names in common use include uridine diphosphoapiose-flavone apiosyltransferase, and UDP-apiose:7-O-(beta-D-glucosyl)-flavone apiosyltransferase. This enzyme participates in flavonoid biosynthesis.
References
- Ortmann R, Sutter A, Grisebach H (1972). "Purification and properties of udpapiose: 7-O-( -D-glucosyl)-flavone apiosyltransferase from cell suspension cultures of parsley". Biochim. Biophys. Acta. 289 (2): 293–302. doi:10.1016/0005-2744(72)90080-0. PMID 4650134.