Estradiol hemisuccinate/progesterone

Estradiol hemisuccinate/progesterone (EHS/P4), sold under the brand name Hosterona, is an injectable combination medication of estradiol hemisuccinate (EHS), an estrogen, and progesterone (P4), a progestogen, which is used to induce withdrawal bleeding in women with non-pregnancy-related amenorrhea (absence of menstruation).[1][2][3][4][5] It is provided in the form of ampoules containing 20 mg/2 mL EHS and 100 mg/2 mL P4 and is administered by intramuscular injection.[3][4][5] The medication is available in Argentina and Paraguay.[1][2][3]

Estradiol hemisuccinate /
progesterone

Estradiol hemisuccinate (top) and progesterone (bottom)
Combination of
Estradiol hemisuccinate	Estrogen
Progesterone	Progestogen
Clinical data
Trade names	Hosterona
Other names	EHS/P4
Routes of administration	Intramuscular injection

See also

• Estradiol/progesterone
• Estradiol benzoate/progesterone
• Estrone/progesterone
• List of combined sex-hormonal preparations

References

1. "Hosterona". Drugs.com. Retrieved 2019-04-12.
2. Sweetman SC, ed. (2009). "Sex hormones and their modulators". Martindale: The Complete Drug Reference (36th ed.). London: Pharmaceutical Press. pp. 2101, 2127. ISBN 978-0-85369-840-1. Estrone [...] Progesterone [...] Multi-ingredient: [...] Arg.: [...] Hosterona
3. "What is HOSTERONA and what is it for?" [Qué es HOSTERONA y para qué sirve?]. MatchMyRx (in Spanish).
4. "Hosterona". Los Medicamentos.
5. "Hosterona". Vademecum Paraguay.