Enkurin

Enkurin is a protein that in humans is encoded by the ENKUR gene.[5][6]

ENKUR
Identifiers
Aliases	ENKUR, C10orf63, CFAP106, enkurin, TRPC channel interacting protein
External IDs	OMIM: 611025 MGI: 1918483 HomoloGene: 17022 GeneCards: ENKUR
Gene location (Human) Chr. Chromosome 10 (human)[1] Band 10p12.1 Start 24,981,979 bp[1] End 25,062,279 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 A3 Start 21,180,731 bp[2] End 21,205,365 bp[2]
Orthologs
Species	Human	Mouse
Entrez	219670	71233
Ensembl	ENSG00000151023	ENSMUSG00000026679
UniProt	Q8TC29	Q6SP97
RefSeq (mRNA)	NM_001270383 NM_145010	NM_027728
RefSeq (protein)	NP_001257312 NP_659447	NP_082004
Location (UCSC)	Chr 10: 24.98 – 25.06 Mb	Chr 2: 21.18 – 21.21 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Enkurin interacts with transient receptor potential canonical (TRPC) cation channels (e.g., TRPC1) and functions as an adaptor protein, tethering signal transduction proteins to TRPC channels.[6]

References

1. GRCh38: Ensembl release 89: ENSG00000151023 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000026679 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: enkurin".
6. Sutton KA, Jungnickel MK, Wang Y, Cullen K, Lambert S, Florman HM (October 2004). "Enkurin is a novel calmodulin and TRPC channel binding protein in sperm". Dev. Biol. 274 (2): 426–35. doi:10.1016/j.ydbio.2004.07.031. PMID 15385169.

Further reading

• Beech DJ (2007). "Canonical transient receptor potential 5". Handb Exp Pharmacol. Handbook of Experimental Pharmacology. 179 (179): 109–23. doi:10.1007/978-3-540-34891-7_6. ISBN 978-3-540-34889-4. PMID 17217053.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.