Elazer R. Edelman

Elazer R. Edelman is an American engineer, scientist and cardiologist. He is the Edward J. Poitras Professor in Medical Engineering and Science at the Massachusetts Institute of Technology (MIT), Professor of Medicine at Harvard Medical School and at Brigham and Women's Hospital (BWH), and a practicing cardiologist at BWH.[1][2] He is the director of MIT's Institute for Medical Engineering and Science (IMES), the Harvard-MIT Biomedical Engineering Center, and the MIT Clinical Research Center. He is also the Program Director of the MIT Graduate Education in Medical Sciences program within the Harvard-MIT Division of Health Sciences and Technology.[3][4] At BWH, he serves as a senior attending physician in the coronary care unit. He is currently the Chief Scientific Advisor for the journal Science Translational Medicine.[5] Edelman has been elected to the American Academy of Arts and Sciences, National Academy of Inventors, National Academy of Engineering and the National Academy of Medicine.[6][7][8][9]

Elazer R. Edelman
CitizenshipAmerican
Alma materMassachusetts Institute of Technology (S.B., S.M., Ph.D.)
Harvard Medical School (M.D.)
Known forAtherosclerotic arterial disease, vascular biology, drug delivery
ChildrenAlex Edelman, AJ Edelman, Austin Edelman
Scientific career
FieldsBiomedical Engineering
Cardiology
Vascular Biology
InstitutionsMassachusetts Institute of Technology
Harvard Medical School
Brigham and Women's Hospital
Doctoral advisorRobert S. Langer
Other academic advisorsMorris J. Karnovsky

Background and education

Edelman was raised in the greater Boston area. He attended the Massachusetts Institute of Technology, where he received bachelor's degrees in Electrical Engineering and Computer Science (EECS) and in Applied Biology, and a master's degree in EECS. He earned his M.D. degree with distinction from Harvard Medical School and Ph.D. in Medical Engineering and Medical Physics within the Harvard-MIT Division of Health Sciences and Technology. He conducted his Ph.D. thesis work under the direction of Robert Langer to define the mathematics of regulated and controlled drug delivery. Edelman completed his medical training at Brigham and Women's Hospital and is board certified in internal medicine and cardiology. Following this, he spent six years as a research fellow under the tutelage of Prof. Morris J. Karnovsky to work on the biology of vascular repair.[10] Edelman and his wife, Cheryl, have 3 children: Alex, A.J., and Austin.

Research

Edelman is a major advocate of multidisciplinary research.[11][12] Through his research centers, he combines teams of clinicians, engineers, and scientists from both academia and industry to create highly effective and clinically relevant solutions to medical problems.[13] Through this approach, Edelman and his students have been credited as some of the key contributors and pioneers of the coronary stent. They critically aided in the development, characterization, and optimization of the first bare-metal stents and subsequent iterations including drug-eluting stents.[14][15] Edelman's research programs fall in the following general categories:[10]

  • polymer-based controlled and modulated drug delivery
  • vascular biology, glycobiology, and growth factor biochemistry
  • tissue engineering
  • biomaterials and tissue interactions
  • device biology

Awards and honors

Edelman has authored or co-authored more than 680 original scientific publications, holds some 80 patents, and has trained more than 300 students and post-doctoral fellows. He has served on several advisory boards including the Science Board to the Food and Drug Administration.[10][16]

Edelman has been elected a fellow of the Association of American Physicians, American College of Cardiology, American Heart Association, American Institute for Medical and Biological Engineering, American Society of Clinical Investigators, American Society of Mechanical Engineers, Association of University Cardiologists, American Academy of Arts and Sciences, National Academy of Engineering, National Academy of Medicine, and National Academy of Inventors. He received the Officer's Cross of the Spanish Order of Civil Merit in 2010.[17]

Selected awards received by Edelman include:

References
  1. "Edelman - Institute for Medical Engineering & Science". Institute for Medical Engineering and Science at MIT. Retrieved 12 January 2016.
  2. "BWH Physician Directory". Brigham and Women's Hospital. Retrieved 12 January 2016.
  3. "Elazer Edelman edelmanlab". Harvard-MIT Biomedical Engineering Center. Retrieved 12 January 2016.
  4. "HST to Offer New Medical Program". The Tech. Retrieved 12 January 2016.
  5. "Editorial staff and scientific advisory boards". Science. Retrieved 12 January 2016.
  6. "Alphabetical List of Active Members" (PDF). American Academy of Arts and Sciences. Retrieved 19 February 2016.
  7. "Current NAI Fellows". National Academy of Inventors. Retrieved 19 February 2016.
  8. "Elazer Edelman - National Academy of Engineering Directory". National Academy of Engineering. Retrieved 12 January 2016.
  9. "Elazer Edelman - Institute of Medicine Profile". National Academy of Medicine. Retrieved 12 January 2016.
  10. "Elazer Edelman - Curriculum Vitae" (PDF). Elazer Edelman. Archived from the original (PDF) on 5 March 2016. Retrieved 12 January 2016.
  11. "Elazer Edelman - How Do We Bridge the Gap in Medical Innovation?". TEDMED. Retrieved 19 February 2016.
  12. "Elazer Edelman - TEDMED Q&A". TEDMED. Retrieved 19 February 2016.
  13. "Taking many forms of expertise to heart". MIT News. Retrieved 12 January 2016.
  14. Hwang, CW; Wu D; Edelman ER (2001). "Physiological transport forces govern drug distribution for stent-based delivery". Circulation. 104 (5): 600–605. doi:10.1161/hc3101.092214. PMID 11479260.
  15. Hwang CW, Levin AD, Jonas M, Li PH, Edelman ER (2005). "Thrombosis modulates arterial drug distribution for drug-eluting stents". Circulation. 111 (13): 1619–26. doi:10.1161/01.CIR.0000160363.30639.37. PMID 15795325.
  16. "Elazer Edelman Bibliography" (PDF). Elazer Edelman. Archived from the original (PDF) on 6 March 2016. Retrieved 12 January 2016.
  17. "HST's Edelman receives award from Spanish government". MIT News. Retrieved 12 January 2016.
  18. "2018 Distinguished Awardees". ACC. Retrieved 29 January 2019.
  19. "Elazer Edelman honored with Cardiovascular Research Foundation career achievement award". MIT News. Retrieved 16 October 2017.
  20. "Bioengineering in Ireland 22". Royal Academy of Medicine in Ireland. Archived from the original on 1 March 2016. Retrieved 19 February 2016.
  21. "Discovery Lecture Series - 2015 Speakers". Vanderbilt University Medical Center. Retrieved 19 February 2016.
  22. "Dean's Distinguished Lecture Series". Weill Cornell Medical College. Retrieved 19 February 2016.
  23. "Awards, Honors, & Grants". Brigham and Women's Hospital. Retrieved 12 January 2016.
  24. "Past Awardees". Society for Biomaterials. Retrieved 12 January 2016.
  25. "Awards, Honors, & Grants". Brigham and Women's Hospital. Retrieved 19 February 2016.
  26. "Jeffrey M. Hoeg Award for Basic Science & Clinical Research". American Heart Association. Archived from the original on 15 September 2015. Retrieved 12 January 2016.
  27. "Excellence in Mentoring Awards Past Recipients". HMS. Retrieved 12 January 2016.
  28. "Awards and Recipients Database". ASTM. Retrieved 12 January 2016.
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