Dolichyl-phosphate D-xylosyltransferase

In enzymology, a dolichyl-phosphate D-xylosyltransferase (EC 2.4.2.32) is an enzyme that catalyzes the chemical reaction

UDP-D-xylose + dolichyl phosphate UDP + dolichyl D-xylosyl phosphate
dolichyl-phosphate D-xylosyltransferase
Identifiers
EC number2.4.2.32
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are UDP-D-xylose and dolichyl phosphate, whereas its two products are UDP and dolichyl D-xylosyl phosphate.

This enzyme belongs to the family of glycosyltransferases, specifically the pentosyltransferases. The systematic name of this enzyme class is UDP-D-xylose:dolichyl-phosphate D-xylosyltransferase.

References

    • Waechter CJ, Lucas JJ, Lennarz WJ (1974). "Evidence for xylosyl lipids as intermediates in xylosyl transfers in hen oviduct membranes". Biochem. Biophys. Res. Commun. 56 (2): 343–50. doi:10.1016/0006-291X(74)90848-1. PMID 4823870.


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