Dinovernavirus

Dinovernavirus is a genus of double-stranded RNA viruses in the family Reoviridae and subfamily Spinareovirinae. Member viruses replicate in a variety of mosquito cell lines. The name is an abbreviation for double-stranded, insect, novem (Latin for nine the number of genome segments), rna virus. There is one species in the genus: the type species Aedes pseudoscutellaris reovirus.[1][2]

Dinovernavirus
Cryo-EM reconstruction of Fako virus capsid showing: turret protein (red), clamp protein (yellow), and homodimer of major capsid protein (blue/purple)
Virus classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Duplornaviricota
Class: Resentoviricetes
Order: Reovirales
Family: Reoviridae
Subfamily: Spinareovirinae
Genus: Dinovernavirus
Type species
Aedes pseudoscutellaris reovirus

Structure

Viruses in Dinovernavirus are non-enveloped. Their capsid is turreted and single shelled with icosahedral geometries and T=2 symmetry. The diameter is around 49–50 nm.[1]

Genome

Genomes are linear and segmented. There are nine segments which code for nine proteins.[1]

Life cycle

Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the double-stranded RNA virus replication model. Double-stranded RNA virus transcription is the method of transcription. The virus exits the host cell by monopartite non-tubule guided viral movement. Mosquito serve as the natural host.[1]

Taxonomy

There is one species in the genus:[2]

  • Aedes pseudoscutellaris reovirus

References
  1. "Viral Zone". ExPASy. Retrieved 13 August 2015.
  2. ICTV. "Virus Taxonomy: 2014 Release". Retrieved 13 August 2015.
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.