Dichroa febrifuga

Dichroa febrifuga (Chinese: 常山; pinyin: chángshān ) is a flowering plant in the family Hydrangeaceae. In the Indonesian language it is called gigil, alternatively tataruman in Sundanese, ramram in Papua, Hom dong (ฮอมดง) in Thai, but Yai khlang yai (ยายคลังใหญ่) in Nakhon Sri Thammarat, Yai Krang (ยายกรัง) in the South, and Hom Kham (ฮอมคำ) in Lanna (Northern Thai).

Dichroa febrifuga
Scientific classification
Kingdom: Plantae
Clade: Tracheophytes
Clade: Angiosperms
Clade: Eudicots
Clade: Asterids
Order: Cornales
Family: Hydrangeaceae
Genus: Dichroa
Species:
D. febrifuga
Binomial name
Dichroa febrifuga
Lour.[1]
A white flowering variety

Traditional Chinese medicine

Dichroa febrifuga is an important herb in traditional Chinese medicine, where it is considered one of the 50 fundamental herbs.[2] The alkaloids febrifugine and isofebrifugine are believed to be responsible for its antimalarial effects.[3] In traditional preparations, it is used in conjunction with other plants such as Glycyrrhiza glabra (licorice), Ziziphus jujube and Zingiber officinale (ginger).[4]

References
  1. "Dichroa febrifuga". Germplasm Resources Information Network (GRIN). Agricultural Research Service (ARS), United States Department of Agriculture (USDA). Retrieved 2008-02-05.
  2. "Dichroa febrifuga - Plants For A Future database report". Retrieved 2008-02-05.
  3. Zhu, Shuren; Meng, Li; Zhang, Quan; Wei, Lai (2006). "Synthesis and evaluation of febrifugine analogues as potential antimalarial agents". Bioorganic & Medicinal Chemistry Letters. 16 (7): 1854–1858. doi:10.1016/j.bmcl.2006.01.009. PMC 2072810. PMID 16434194.
  4. Rasoanaivo, Philippe; Wright, Colin W; Willcox, Merlin L; Gilbert, Ben (2011). "Whole plant extracts versus single compounds for the treatment of malaria: Synergy and positive interactions". Malaria Journal. 10 (Suppl 1): S4. doi:10.1186/1475-2875-10-S1-S4. PMC 3059462. PMID 21411015.


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