Demethylsterigmatocystin 6-O-methyltransferase
In enzymology, a demethylsterigmatocystin 6-O-methyltransferase (EC 2.1.1.109) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + 6-demethylsterigmatocystin S-adenosyl-L-homocysteine + sterigmatocystin
| demethylsterigmatocystin 6-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.109 | ||||||||
| CAS number | 123516-47-2 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are S-adenosyl methionine and 6-demethylsterigmatocystin, whereas its two products are S-adenosylhomocysteine and sterigmatocystin.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:6-demethylsterigmatocystin 6-O-methyltransferase. Other names in common use include demethylsterigmatocystin methyltransferase, and O-methyltransferase I.
References
- Yabe K, Ando Y, Hashimoto J, Hamasaki T (1989). "Two distinct O-methyltransferases in aflatoxin biosynthesis". Appl. Environ. Microbiol. 55 (9): 2172–7. PMC 203052. PMID 2802602.
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