Dehydrocholic acid

Dehydrocholic acid is a synthetic bile acid, manufactured by the oxidation of cholic acid. It acts as a hydrocholeretic, increasing bile output to clear increased bile acid load.[1]

Dehydrocholic acid
Names
IUPAC name
(4R)-4-[(5S,8R,9S,10S,13R,14S,17R)-10,13-Dimethyl-3,7,12-trioxo-1,2,4,5,6,8,9,11,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-17-yl]pentanoic acid
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.001.215
KEGG
UNII
Properties
C24H24O5
Molar mass 392.451 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

  1. Yousef IM, Barnwell SG, Tuchweber B, Weber A, Roy CC (1987). "Effect of complete sulfation of bile acids on bile formation in rats". Hepatology. 7 (3): 535–42. doi:10.1002/hep.1840070320. PMID 3570165.


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