Decyl glucoside

Decyl glucoside is a mild non-ionic surfactant used in cosmetic formularies,[1] including baby shampoo and in products for individuals with a sensitive skin. Many natural personal care companies use this cleanser because it is plant-derived, biodegradable, and gentle for all hair types.

Decyl glucoside

Names
IUPAC name (2R,3R,4S,5S,6R)-2-Decoxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol
Identifiers
CAS Number	58846-77-8
3D model (JSmol)	Interactive image
ChemSpider	55973
ECHA InfoCard	100.055.863
PubChem CID	62142
UNII	Z17H97EA6Y
CompTox Dashboard (EPA)	DTXSID2041208
InChI InChI=1/C16H32O6/c1-2-3-4-5-6-7-8-9-10-21-16-15(20)14(19)13(18)12(11-17)22-16/h12-20H,2-11H2,1H3/t12-,13-,14+,15-,16-/m1/s1 Key: JDRSMPFHFNXQRB-IBEHDNSVBI
SMILES O(CCCCCCCCCC)[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)CO
Properties
Chemical formula	C16H32O6
Molar mass	320.426 g·mol^−1
Hazards
Safety data sheet	MSDS
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

In 2017, the American Contact Dermatitis society named alkyl glucosides, a class of compounds including decyl, lauryl, cetearyl, and coco glucosides, the Allergen of the Year, with decyl glucoside named as "the most common one in the class of alkyl glucosides to cause allergic contact dermatitis."[2]

Synthesis

Decyl glucoside is produced by the reaction of glucose from corn starch with the fatty alcohol decanol, which is derived from coconut.

See also

• Lauryl glucoside
• Octyl glucoside

References

1. Fiume MM, Heldreth B, Bergfeld WF, Belsito DV, Hill RA, Klaassen CD, Liebler D, Marks JG Jr, Shank RC, Slaga TJ, Snyder PW, Andersen FA. Safety assessment of decyl glucoside and other alkyl glucosides as used in cosmetics. Int J Toxicol. 2013 Sep-Oct;32(5 Suppl):22S-48S. doi:10.1177/1091581813497764 PMID 24174472
2. Mowad, Christen Maria (2017-11-17). "2017 Top Stories in Dermatology: Allergen of the Year—Alkyl Glucoside". Dermatology.