DNER

Delta and Notch-like epidermal growth factor-related receptor is a protein that in humans is encoded by the DNER gene.[5][6][7]

DNER
Identifiers
Aliases	DNER, UNQ26, bet, delta/notch like EGF repeat containing
External IDs	OMIM: 607299 MGI: 2152889 HomoloGene: 26722 GeneCards: DNER
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q36.3 Start 229,357,629 bp[1] End 229,714,555 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1|1 C5 Start 84,369,839 bp[2] End 84,696,221 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • clathrin binding • calcium ion binding • GO:0001948 protein binding • transmembrane signaling receptor activity • Notch binding Cellular component • integral component of membrane • neuronal cell body • cell membrane • dendrite • early endosome • membrane Biological process • Notch receptor processing • synapse assembly • central nervous system development • neuron migration • endocytosis • glial cell differentiation • skeletal muscle fiber development • Notch signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	92737	227325
Ensembl	ENSG00000187957	ENSMUSG00000036766
UniProt	Q8NFT8	Q8JZM4
RefSeq (mRNA)	NM_139072	NM_152915
RefSeq (protein)	NP_620711	NP_690879
Location (UCSC)	Chr 2: 229.36 – 229.71 Mb	Chr 1: 84.37 – 84.7 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000187957 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000036766 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Eiraku M, Hirata Y, Takeshima H, Hirano T, Kengaku M (Jul 2002). "Delta/notch-like epidermal growth factor (EGF)-related receptor, a novel EGF-like repeat-containing protein targeted to dendrites of developing and adult central nervous system neurons". J Biol Chem. 277 (28): 25400–7. doi:10.1074/jbc.M110793200. PMID 11950833.
6. Nishizumi H, Komiyama T, Miyabayashi T, Sakano S, Sakano H (May 2002). "BET, a novel neuronal transmembrane protein with multiple EGF-like motifs". NeuroReport. 13 (6): 909–15. doi:10.1097/00001756-200205070-00035. PMID 11997712. S2CID 8325151.
7. "Entrez Gene: DNER delta/notch-like EGF repeat containing".

Further reading

• Sanger Centre, The; Washington University Genome Sequencing Cente, The (1999). "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. doi:10.1038/nature03466. PMID 15815621.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Ramachandran P, Boontheung P, Xie Y, et al. (2006). "Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry". J. Proteome Res. 5 (6): 1493–503. doi:10.1021/pr050492k. PMID 16740002.