DEFB127

Beta-defensin 127 is a protein that in humans is encoded by the DEFB127 gene.[3][4]

DEFB127
Identifiers
AliasesDEFB127, C20orf73, DEF-27, DEFB-27, DEFB27, bA530N10.2, hBD-27, defensin beta 127
External IDsHomoloGene: 89142 GeneCards: DEFB127
Gene location (Human)
Chr.Chromosome 20 (human)[1]
Band20p13Start157,454 bp[1]
End159,163 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

140850

n/a

Ensembl

ENSG00000088782

n/a

UniProt

Q9H1M4

n/a

RefSeq (mRNA)

NM_139074

n/a

RefSeq (protein)

NP_620713

n/a

Location (UCSC)Chr 20: 0.16 – 0.16 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Defensins are cysteine-rich cationic polypeptides that are important in the immunologic response to invading microorganisms. The protein encoded by this gene is secreted and is a member of the beta defensin protein family. Beta defensin genes are found in several clusters throughout the genome, with this gene mapping to a cluster at 20p13.[4]

References

  1. GRCh38: Ensembl release 89: ENSG00000088782 - Ensembl, May 2017
  2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. Schutte BC, Mitros JP, Bartlett JA, Walters JD, Jia HP, Welsh MJ, Casavant TL, McCray PB Jr (Feb 2002). "Discovery of five conserved beta -defensin gene clusters using a computational search strategy". Proc Natl Acad Sci U S A. 99 (4): 2129–33. doi:10.1073/pnas.042692699. PMC 122330. PMID 11854508.
  4. "Entrez Gene: DEFB127 defensin, beta 127".

Further reading


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