D-tryptophan N-malonyltransferase

In enzymology, a D-tryptophan N-malonyltransferase (EC 2.3.1.112) is an enzyme that catalyzes the chemical reaction

malonyl-CoA + D-tryptophan CoA + N2-malonyl-D-tryptophan
D-tryptophan N-malonyltransferase
Identifiers
EC number2.3.1.112
CAS number94490-01-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are malonyl-CoA and D-tryptophan, whereas its two products are CoA and N2-malonyl-D-tryptophan.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:D-tryptophan N-malonyltransferase.

References

    • Matern U, Feser C, Heller W (1984). "N-malonyltransferases from peanut". Arch. Biochem. Biophys. 235 (1): 218–27. doi:10.1016/0003-9861(84)90271-6. PMID 6497391.


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