Cyclohexane-1,3-dione hydrolase

In enzymology, a cyclohexane-1,3-dione hydrolase (EC 3.7.1.10) is an enzyme that catalyzes the chemical reaction

cyclohexane-1,3-dione + H2O 5-oxohexanoate
cyclohexane-1,3-dione hydrolase
Identifiers
EC number3.7.1.10
CAS number123516-46-1
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are cyclohexane-1,3-dione and H2O, whereas its product is 5-oxohexanoate.

This enzyme belongs to the family of hydrolases, specifically those acting on carbon-carbon bonds in ketonic substances. The systematic name of this enzyme class is cyclohexane-1,3-dione acylhydrolase (decyclizing). This enzyme is also called 1,3-cyclohexanedione hydrolase.

References

    • Dangel W, Tschech A, Fuchs G (1989). "Enzyme-reactions involved in anaerobic cyclohexanol metabolism by a denitrifying Pseudomonas species". Arch. Microbiol. 152 (3): 273–279. doi:10.1007/BF00409663. PMID 2505723.


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