Chloral hydrate/magnesium sulfate/pentobarbital

Chloral hydrate/magnesium sulfate/pentobarbital sodium, brand name Equithesin, is a combination anesthetic agent used as a general anesthetic in horses.[1] It is administered intravenously to effect. For many years, it was the most commonly used injectable anesthetic in horses. Newer anesthetic agents such as injectable barbiturates, alpha-2 agonists, cyclohexylamines, and inhalants gradually replaced Equithesin. The drug has been off the market and unavailable for decades.

Chloral hydrate/magnesium sulfate/pentobarbital
Combination of
Chloral hydrateSedative
Magnesium sulfateNeuromuscular blocker
PentobarbitalBarbiturate
Clinical data
Trade namesEquithesin

This combination anesthetic agent contains 42.5 mg chloral hydrate, 21.2 mg magnesium sulfate and 8.86 mg pentobarbital per milliliter.[2]

References
  1. Studdert VP, Gay CC, Blood DC, eds. (2012). "Equithesin". Saunders comprehensive veterinary dictionary (4th ed.). Edinburgh: Elsevier Saunders. p. 393. ISBN 9780702047442.
  2. Posner LP, Burns P (2009). "Chapter 11. Injectable anesthetic agents. Miscellaneous intravenous anesthetics". In Riviere JE, Papich MG (eds.). Veterinary pharmacology and therapeutics (9th ed.). Ames, Iowa: Wiley-Blackwell. p. 291–292. ISBN 978-0-8138-2061-3.


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