CDP-acylglycerol O-arachidonoyltransferase
In enzymology, a CDP-acylglycerol O-arachidonoyltransferase (EC 2.3.1.70) is an enzyme that catalyzes the chemical reaction
- arachidonoyl-CoA + CDP-acylglycerol CoA + CDP-diacylglycerol
| CDP-acylglycerol O-arachidonoyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.70 | ||||||||
| CAS number | 70771-22-1 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are arachidonoyl-CoA and CDP-acylglycerol, whereas its two products are CoA and CDP-diacylglycerol.
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is arachidonoyl-CoA:CDP-acylglycerol O-arachidonoyltransferase. Other names in common use include CDP-acylglycerol O-arachidonyltransferase, and arachidonyl-CoA:CDP-acylglycerol O-arachidonyltransferase. This enzyme participates in glycerophospholipid metabolism.
References
- Thompson W, MacDonald G (1979). "Isolation of a specific arachidonoyl coenzyme A: cytidine diphosphate monoacylglycerol acyltransferase". J. Biol. Chem. 254 (9): 3311–4. PMID 429352.
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