BOC (gene)

Brother of CDO is a protein that in humans is encoded by the BOC gene.[5][6]

BOC
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesBOC, CDON2, BOC cell adhesion associated, oncogene regulated
External IDsOMIM: 608708 MGI: 2151153 HomoloGene: 32819 GeneCards: BOC
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3q13.2Start113,211,003 bp[1]
End113,287,459 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

91653

117606

Ensembl

ENSG00000144857

ENSMUSG00000022687

UniProt

Q9BWV1

Q6AZB0

RefSeq (mRNA)

NM_172506

RefSeq (protein)

NP_766094

Location (UCSC)Chr 3: 113.21 – 113.29 MbChr 16: 44.49 – 44.56 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

CDON (MIM 608707) and BOC are cell surface receptors of the immunoglobulin (Ig)/fibronectin type III (FNIII; see MIM 135600) repeat family involved in myogenic differentiation. CDON and BOC are coexpressed during development, form complexes with each other in a cis fashion, and are related to each other in their ectodomains, but each has a unique long cytoplasmic tail.[supplied by OMIM][6]

Interactions

BOC (gene) has been shown to interact with CDON.[5]

References

  1. GRCh38: Ensembl release 89: ENSG00000144857 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000022687 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Kang JS, Mulieri PJ, Hu Y, Taliana L, Krauss RS (Jan 2002). "BOC, an Ig superfamily member, associates with CDO to positively regulate myogenic differentiation". EMBO J. 21 (1–2): 114–24. doi:10.1093/emboj/21.1.114. PMC 125805. PMID 11782431.
  6. "Entrez Gene: BOC Boc homolog (mouse)".

Further reading


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