Amsler sign

Amsler sign also known as Amsler–Verrey sign is the name of the diagnostic finding seen in people with Fuchs heterochromic iridocyclitis (FHI). It is described as presence of blood (hyphema) in the aspirated vitreous fluid, in paracentesis of the anterior chamber, and is caused due to iris atrophy usually seen in FHI and exposure of the fragile iris vasculature to the vitreous fluid. The sudden change of pressure in the anterior chamber upon suction induced by the paracentesis, or during a cataract surgery,[1] causes bursting of the fragile superficial iris capillaries resulting in micro-bleeding. This is one clinical diagnostic sign of FHI.[1][2][3]

Amsler sign
SynonymsAmsler–Verrey sign
PurposeDiagnosing Fuchs heterochromic iridocyclitis

History

This sign is named after the Swiss ophthalmologist Marc Amsler (February 15, 1891 – May 3, 1968).[2][4] It is sometimes referred to as Amsler–Verrey sign to acknowledge the contribution of another Swiss ophthalmologist, Florian Verrey (1911–1976).[5]

Sources
  1. Sathish Srinivasan; Douglas Lyall; Christine Kiire (16 July 2010). "Amsler-Verrey sign during cataract surgery in Fuchs heterochromic uveitis". Case Reports. BMJ Case Reports. 2010: bcr1120092456. doi:10.1136/bcr.11.2009.2456. PMC 3038033. PMID 22767537.
  2. mrcophth. "Marc Amsler". Retrieved 15 December 2010.
  3. Pammal T. Ashwin; Katya Tambe; Mike Quinlan (September 2006). "Unusual presentation of Amsler's sign in Fuchs' heterochromic uveitis": 1579–80. Retrieved 15 December 2010. Cite journal requires |journal= (help)
  4. Ole Daniel Enersen. "Marc Amsler". Who Named It?. Retrieved 15 December 2010.
  5. Ole Daniel Enersen. "Florian Verrey". Who Named It?. Retrieved 15 December 2010.
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