Adiphenine

Adiphenine is an inhibitor of nicotinic receptors.[1]

Adiphenine

Names
IUPAC name 2-(Diethylamino)ethyl 2,2-diphenylacetate
Other names Diphacil
Identifiers
CAS Number	64-95-9
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL353846
ChemSpider	1953
ECHA InfoCard	100.000.545
EC Number	200-599-0
KEGG	D02772
MeSH	C084829
PubChem CID	2031
UNII	YKG6OR043Q
CompTox Dashboard (EPA)	DTXSID0022561
InChI InChI=1S/C20H25NO2/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14,19H,3-4,15-16H2,1-2H3 Key: JGOAIQNSOGZNBX-UHFFFAOYSA-N InChI=1/C20H25NO2/c1-3-21(4-2)15-16-23-20(22)19(17-11-7-5-8-12-17)18-13-9-6-10-14-18/h5-14,19H,3-4,15-16H2,1-2H3 Key: JGOAIQNSOGZNBX-UHFFFAOYAN
SMILES CCN(CC)CCOC(=O)C(C1=CC=CC=C1)C2=CC=CC=C2
Properties
Chemical formula	C20H25NO2
Molar mass	311.425 g·mol^−1
Melting point	112–114 °C (234–237 °F; 385–387 K)
Hazards
Lethal dose or concentration (LD, LC):
LD50 (median dose)	290 mg/kg (mouse; intraperitoneal)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

See also

• Dicycloverine

References

1. Spitzmaul, G; Gumilar, F; Dilger, JP; Bouzat, C (2009). "The local anaesthetics proadifen and adiphenine inhibit nicotinic receptors by different molecular mechanisms". British Journal of Pharmacology. 157 (5): 804–17. doi:10.1111/j.1476-5381.2009.00214.x. PMC 2721265. PMID 19422391.