Adam Heller

Adam Heller (born June 25, 1933) is an Israeli-American engineer, Chief Science Officer of SynAgile Corp. and Ernest Cockrell Sr. Chair Emeritus of Engineering at The University of Texas at Austin. He consults to Abbott Diabetes Care, Inc. of Alameda, California, the maker of the Freestyle line of products.

Adam Heller
President George W. Bush presents the 2007 National Medal for Technology and Innovation to Dr. Adam Heller of the University of Texas at Austin at a ceremony in September 2008.
Born (1933-06-25) June 25, 1933
Cluj, Romania
NationalityAmerican
Alma materHebrew University
Scientific career
FieldsChemical Engineering
InstitutionsBell Laboratories
GTE Laboratories
University of Texas at Austin
Doctoral advisorErnst David Bergmann

Biography

Holocaust

Adam Heller was born in 1933 to Jewish parents in Cluj, Kingdom of Romania. In 1944, following the Second Vienna Award, the Hungarian administration confiscated his family's property, and they were forcibly relocated along with more than 18,000 other Jews to the Kolozsvár Ghetto within the walls of the Iris Brickyard.[1] In late May of the same year, the prisoners of the ghetto at Kolozsvár were transported out of the ghetto as part of the Nazi Final Solution. Heller and his immediate family survived on Kastner's train.[2][3] In 1945, he arrived in British Mandate Palestine, which became the State of Israel in 1948.

Education

Heller received his M.Sc. and Ph.D. from Hebrew University in 1961, where he studied under Ernst David Bergmann.[4] After post-doctoral research at the University of California, Berkeley (1962–1963) and at Bell Laboratories in Murray Hill, New Jersey (1963–1964),

Inorganic liquid lasers and the lithium thionyl chloride battery

At GTE Laboratories in Bayside, New York then in Waltham, Massachusetts (1964–1975) he developed one of the earliest liquid lasers, the first based on Nd3+ solutions in oxyhalide solvents, then with James J. Auborn the lithium thionyl chloride non-rechargeable battery with the highest energy density, 20+ year shelf life operating at the lowest and highest temperatures on earth.

Semiconductor liquid junction solar cells

At Bell Laboratories (1975–1988),[5] where he headed the Electronic Materials Research Department (1977–1988) his colleagues developed elements of high-speed electronic and optoelectronic interconnection technologies while Heller developed the first semiconductor liquid junction solar cells with efficiencies greater than 10%.

Glucose monitoring electrochemical systems for diabetes management

While a professor of engineering at The University of Texas at Austin (1988–2020),[6][7] he and his son Ephraim Heller co-founded TheraSense in 1996, now part of Abbott Diabetes Care, Inc. He was the first Chief Technical Officer of the company.[8] The FreeStyle™ system of TheraSense, a micro-coulometer released in 2000, made the monitoring of blood glucose painless by accurately monitoring the glucose concentration in 300 nanoliters of blood.[9] With more than a billion units produced annually, FreeStyle™ became the highest impact nanotechnology or micro-fluidic device.[10] The FreeStyle Libre™ continuous glucose monitoring system [11] of Abbott Diabetes Care, is the world's most widely used diabetes management system and is based on the electrical wiring of enzymes, science and technology of which were created by Heller.[12][13][14]

Continuous oral delivery of L-DOPA for managing Parkinson's disease

Heller serves as Chief Scientific Officer of Synagile Corporation, a venture developing a continuous oral L-DOPA systems for managing advanced Parkinson's disease.

Research

His study of the physical chemistry of inorganic oxyhalide solutions resulted in the first neodymium liquid lasers (1964–1967).[15] It also resulted in one of the earliest lithium batteries, the globally manufactured lithium thionyl chloride battery (1973) used in implanted medical and in defense systems where greater than a 20-year shelf life, high energy density, or operation at any temperature encountered on Earth are required.[16]

His studies of photoelectrochemical solar cells resulted in 11.5% efficient solar cells (1980)[17] and in 12% efficient hydrogen evolving photoelectrodes.[18] His related studies with Heinz Gerischer of photoelectrocatalysis established that the rate of photo-assisted oxidation of organic matter on photocatalytic titanium dioxide particles was controlled by the rate of reduction of adsorbed oxygen by trapped electrons.[19]

He established the field of electrical wiring of enzymes (1988–2005),[20] the science and engineering of the transduction of the turnover rates of electron-transferring reactions of enzymes to electrical currents without use of diffusing oxidants or reductants. His study of the electrical wiring of glucose oxidase enables the continuous and bloodless glucose monitoring with subcutaneously implanted sensors.[21] It is the core technology of the FreeStyle Libre™ system of Abbott Diabetes Care, having a glucose concentration transmitting skin adhered patch that is replaced every two weeks by the user. Unlike earlier monitors, it operates without periodic blood-requiring calibrations.

As of October 2019, Heller and his co-inventors' patents and publications have been cited according to Google Scholar citations 122,210 times and their h-index is 169.

Awards

In 2008, he was awarded the National Medal of Technology and Innovation for the year 2007, the highest technology award in the United States.[22] Earlier, in 1987 he was elected to the U.S. National Academy of Engineering[23] and in 2009 to the American Academy of Arts and Sciences.[24] In 2015, he became the 78th Honorary Member of The Electrochemical Society.[25] He was named Guest Professor of the Collège de France in 1982 and received honorary doctorates from Uppsala University in Sweden in 1991[26] and from Queen’s College of the City University of New York in 2008.[5] His medals include the Spiers Medal and the Faraday Medal of the Royal Society of Chemistry, UK,[27] the Vittorio De Nora Gold Medal of The Electrochemical Society[28] and the Fresenius Gold Medal and Prize of the Society of German Chemists[29] and the Torbern Bergman Medal of the Swedish Chemical Society, which he shared with Allen J. Bard.[30] His awards include the Battery Research Award, the Grahame Award and the Heinz Gerischer Prize of The Electrochemical Society,[31][32][33] and the Chemistry of Materials and Creative Invention Awards of the American Chemical Society[34] and the American Institute of Chemical Engineers Service to Society Award,[35] and its Chemical Engineering Practice Award.[36]He was named The 2019 Honorable Member of the Israel Chemical Society.

References
  1. Braham, Randolph (2000). The Politics of Genocide: The Holocaust in Hungary. Detroit: Wayne State University Press. p. 129.
  2. Löb, Ladislaus (2009). Rezso Kasztner: The Daring Rescue of Hungarian Jews: A Survivor's Account. New York: Pimlico. p. 97.
  3. Landé, Peter; Field, Joyce (August 2008). "The Rudolph Kasztner Transports". jewishgen.org. Retrieved 16 June 2014.
  4. Society for Electroanalytical Chemistry. "Adam Heller - 2004 Reilly Award". Retrieved 18 November 2013.
  5. Michael J. Fox Foundation. "Parkinson's Researcher Profile: Adam Heller, PhD". Retrieved 18 November 2013.
  6. The University of Texas at Austin. "Experts Guide: Adam Heller". Retrieved 18 November 2013.
  7. "UT-Austin fires chemical engineering professor for kissing colleague on lips - The Daily Texan". www.dailytexanonline.com. Retrieved 2020-11-13.
  8. Bloomberg Businessweek. "Executive Profile: Adam Heller, PhD". Retrieved 18 November 2013.
  9. Abbott Laboratories. "Freestyle Lite FAQs". Retrieved 18 November 2013.
  10. Abbott Laboratories. "Abbott Medical Devices: Overview". Retrieved 18 November 2013.
  11. Abbott Diabetes Care (1 November 2016). "FreeStyle Libre". Retrieved 1 November 2016.
  12. The University of Texas at Austin, Cockrell School of Engineering. "A Patented Success". Retrieved 21 November 2013.
  13. Heller, A. and B. Feldman (2010). "Electrochemistry in Diabetes Management." Acc. Chem. Res., 43: 963-973
  14. Heller, A. and B. Feldman (2008). "Electrochemical Glucose Sensors and Their Applications in Diabetes Management." Chem. Rev. (Washington, DC, U.S.) 108 (ACS): 2482-2505
  15. Heller, Adam (1968). "Liquid lasers—Design of neodymium-based inorganic ionic systems". Journal of Molecular Spectroscopy. 28: 101. doi:10.1016/0022-2852(68)90112-4.
  16. Heller, Adam (25 November 1975). "Electrochemical Cell". United States Patent. Retrieved 18 November 2013.
  17. Heller, Adam; Vadimsky, Richard (1981). "Efficient Solar to Chemical Conversion: 12% Efficient Photoassisted Electrolysis in the [p-type InP(Ru)]/HCl-KCl/Pt(Rh) Cell". Physical Review Letters. 46 (17): 1153. doi:10.1103/PhysRevLett.46.1153.
  18. Heller, Adam (1984). "Hydrogen Evolving Solar Cells". Catalysis Reviews. 26 (3–4): 655. doi:10.1080/01614948408064730.
  19. Gerischer, Heinz; Heller, Adam (1991). "The role of oxygen in photooxidation of organic molecules on semiconductor particles". The Journal of Physical Chemistry. 95 (13): 5261. doi:10.1021/j100166a063.
  20. Heller, Adam (1990). "Electrical wiring of redox enzymes". Accounts of Chemical Research. 23 (5): 128. doi:10.1021/ar00173a002.
  21. Heller, A (1999). "Implanted electrochemical glucose sensors for the management of diabetes". Annual Review of Biomedical Engineering. 1: 153–75. doi:10.1146/annurev.bioeng.1.1.153. PMID 11701486.
  22. United States Patent and Trademark Office. "2007 Laureates". Retrieved 18 November 2013.
  23. National Academy of Engineering. "Member Directory". Retrieved 18 November 2013.
  24. American Academy of Arts and Sciences. "Index of Active Members" (PDF). Retrieved 18 November 2013.
  25. "Honorary Membership". ECS. Retrieved 2016-11-01.
  26. http://www.uu.se/en/about-uu/traditions/prizes/honorary-doctorates/
  27. Royal Academy of Chemistry. "Previous Winners". Retrieved 18 November 2013.
  28. The Electrochemical Society. "Vittorio de Nora Award Recipients". Archived from the original on 25 June 2013. Retrieved 18 November 2013.
  29. The University of Texas at Austin, Department of Chemical Engineering. "Faculty Directory: Adam Heller, PhD". Retrieved 18 November 2013.
  30. The Swedish Chemical Society. "Analysdagarna 2014". Retrieved 18 November 2013.
  31. The Electrochemical Society. "Battery Division Research Award Recipients". Retrieved 18 November 2013.
  32. "David C. Grahame Award". ECS. Retrieved 2016-11-01.
  33. "Europe Section Heinz Gerischer Award". ECS. Retrieved 2016-11-01.
  34. American Chemical Society. "ACS Award for Creative Invention". Retrieved 18 November 2013.
  35. "Award for Service to Society | AIChE". www.aiche.org. Retrieved 2016-11-01.
  36. American Institute of Chemical Engineers. "Lawrence B. Evans Award in Chemical Engineering Practice". Retrieved 18 November 2013.
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