ASXL3

Additional sex combs like 3 (Drosophila) is a protein that in humans is encoded by the ASXL3 gene.[5]

ASXL3
Identifiers
Aliases	ASXL3, BRPS, KIAA1713, additional sex combs like 3, transcriptional regulator, ASXL transcriptional regulator 3
External IDs	OMIM: 615115 MGI: 2685175 HomoloGene: 19371 GeneCards: ASXL3
Gene location (Human) Chr. Chromosome 18 (human)[1] Band 18q12.1 Start 33,578,219 bp[1] End 33,751,195 bp[1]
Gene location (Mouse) Chr. Chromosome 18 (mouse)[2] Band 18|18 A2 Start 22,344,246 bp[2] End 22,530,227 bp[2]
Gene ontology Molecular function • metal ion binding • DNA binding • chromatin binding • peroxisome proliferator activated receptor binding Cellular component • cell nucleus • nuclear chromatin • PR-DUB complex Biological process • regulation of transcription, DNA-templated • transcription, DNA-templated • animal organ morphogenesis • positive regulation of transcription from RNA polymerase II promoter Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	80816	211961
Ensembl	ENSG00000141431	ENSMUSG00000045215
UniProt	Q9C0F0	Q8C4A5
RefSeq (mRNA)	NM_030632	NM_001167777
RefSeq (protein)	NP_085135	NP_001161249
Location (UCSC)	Chr 18: 33.58 – 33.75 Mb	Chr 18: 22.34 – 22.53 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000141431 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000045215 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: Additional sex combs like 3 (Drosophila)".

Further reading

• Fisher CL, Randazzo F, Humphries RK, Brock HW (March 2006). "Characterization of Asxl1, a murine homolog of Additional sex combs, and analysis of the Asx-like gene family". Gene. 369: 109–18. doi:10.1016/j.gene.2005.10.033. PMID 16412590.
• Katoh M, Katoh M (June 2004). "Identification and characterization of ASXL3 gene in silico". International Journal of Oncology. 24 (6): 1617–22. PMID 15138607.