6-O-methylnorlaudanosoline 5'-O-methyltransferase
In enzymology, a 6-O-methylnorlaudanosoline 5'-O-methyltransferase (EC 2.1.1.121) is an enzyme that catalyzes the chemical reaction
- S-adenosyl-L-methionine + 6-O-methylnorlaudanosoline S-adenosyl-L-homocysteine + nororientaline
| 6-O-methylnorlaudanosoline 5'-O-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.1.1.121 | ||||||||
| CAS number | 89511-99-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are S-adenosyl methionine and 6-O-methylnorlaudanosoline, whereas its two products are S-adenosylhomocysteine and nororientaline.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:6-O-methylnorlaudanosoline 5'-O-methyltransferase. This enzyme participates in alkaloid biosynthesis i.
References
- Rueffer M, Nagakura N, Zenk MH (1983). "A highly specific O-methyltransferase for nororientaline synthesis isolated from Argemone platyceras cell cultures". Planta Med. 49 (12): 196–198. doi:10.1055/s-2007-969849. PMID 17405051.
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