2-nitroimidazole nitrohydrolase

2-nitroimidazole nitrohydrolase (EC 3.5.99.9, NnhA, 2NI nitrohydrolase, 2NI denitrase) is an enzyme with systematic name 2-nitroimidazole nitrohydrolase.[1] This enzyme catalyses the following chemical reaction

2-nitroimidazole + H2O imidazol-2-one + nitrite
2-nitroimidazole nitrohydrolase
Identifiers
EC number3.5.99.9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

This enzyme is present in the soil bacterium Mycobacterium sp. JS330

References

  1. Qu Y, Spain JC (April 2011). "Catabolic pathway for 2-nitroimidazole involves a novel nitrohydrolase that also confers drug resistance". Environmental Microbiology. 13 (4): 1010–7. doi:10.1111/j.1462-2920.2010.02406.x. PMID 21244596.
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