2-nitroimidazole nitrohydrolase
2-nitroimidazole nitrohydrolase (EC 3.5.99.9, NnhA, 2NI nitrohydrolase, 2NI denitrase) is an enzyme with systematic name 2-nitroimidazole nitrohydrolase.[1] This enzyme catalyses the following chemical reaction
- 2-nitroimidazole + H2O imidazol-2-one + nitrite
2-nitroimidazole nitrohydrolase | |||||||||
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Identifiers | |||||||||
EC number | 3.5.99.9 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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This enzyme is present in the soil bacterium Mycobacterium sp. JS330
References
- Qu Y, Spain JC (April 2011). "Catabolic pathway for 2-nitroimidazole involves a novel nitrohydrolase that also confers drug resistance". Environmental Microbiology. 13 (4): 1010–7. doi:10.1111/j.1462-2920.2010.02406.x. PMID 21244596.
External links
- 2-nitroimidazole+nitrohydrolase at the US National Library of Medicine Medical Subject Headings (MeSH)
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